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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZC3HC1 All Species: 22.73
Human Site: S290 Identified Species: 45.45
UniProt: Q86WB0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86WB0 NP_057562.3 502 55262 S290 G F Q Q I E S S M T D L D A S
Chimpanzee Pan troglodytes XP_001156206 502 55199 S290 G F Q Q I E S S M T D L D A S
Rhesus Macaque Macaca mulatta XP_001094530 502 55199 S290 G F Q Q I E S S M T D L D A S
Dog Lupus familis XP_532428 589 65257 S377 G F Q Q I E S S M T D L D A S
Cat Felis silvestris
Mouse Mus musculus Q80YV2 501 55178 S289 G F Q Q I E S S M T D L E A S
Rat Rattus norvegicus NP_001120765 501 55306 S289 G F Q Q M E S S M T D L E A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510194 625 67731 A349 G F Q Q I E S A L S D L E V S
Chicken Gallus gallus XP_414975 484 53210 G275 M R K V G L W G F H Q L E S A
Frog Xenopus laevis Q6P7H4 477 53273 M268 I I N C P R C M R K V G L W A
Zebra Danio Brachydanio rerio NP_001070846 492 54140 A281 N F Y Q M D T A L E A E N P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001200598 300 33790 G92 S C K E V L Y G G L P P K W E
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001141693 698 76497 D380 Q L F K L I S D S N R Q D D Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98.8 79.2 N.A. 85 85.8 N.A. 53.4 62.3 52.1 43 N.A. N.A. N.A. N.A. 26.4
Protein Similarity: 100 99.1 99 81.4 N.A. 91 91.2 N.A. 63.3 74.5 65.3 61.9 N.A. N.A. N.A. N.A. 38
P-Site Identity: 100 100 100 100 N.A. 93.3 86.6 N.A. 66.6 6.6 0 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 33.3 6.6 53.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. 22 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 35.5 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 17 0 0 9 0 0 50 17 % A
% Cys: 0 9 0 9 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 9 0 0 59 0 42 9 0 % D
% Glu: 0 0 0 9 0 59 0 0 0 9 0 9 34 0 9 % E
% Phe: 0 67 9 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 59 0 0 0 9 0 0 17 9 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 9 9 0 0 50 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 17 9 0 0 0 0 0 9 0 0 9 0 0 % K
% Leu: 0 9 0 0 9 17 0 0 17 9 0 67 9 0 0 % L
% Met: 9 0 0 0 17 0 0 9 50 0 0 0 0 0 0 % M
% Asn: 9 0 9 0 0 0 0 0 0 9 0 0 9 0 0 % N
% Pro: 0 0 0 0 9 0 0 0 0 0 9 9 0 9 9 % P
% Gln: 9 0 59 67 0 0 0 0 0 0 9 9 0 0 9 % Q
% Arg: 0 9 0 0 0 9 0 0 9 0 9 0 0 0 0 % R
% Ser: 9 0 0 0 0 0 67 50 9 9 0 0 0 9 59 % S
% Thr: 0 0 0 0 0 0 9 0 0 50 0 0 0 0 0 % T
% Val: 0 0 0 9 9 0 0 0 0 0 9 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 17 0 % W
% Tyr: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _